(CNN) - Meryl Streep was honored at the Golden Globes for a lifetime of notable work, and she used her acceptance speech to make a sustained attack on Donald Trump.
In her nearly six-minute address while accepting the Cecil B. DeMille Award from the Hollywood Foreign Press Association, the actress highlighted the importance of the "most vilified segments in American society right now" -- "Hollywood, foreigners and the press."
Without referencing him by name, the actress blasted Trump for publicly mocking a reporter with a disability.
In an interview with the The New York Times Monday morning, Trump said he was "not surprised" by the criticism from "liberal movie people."
"Hollywood is crawling with outsiders and foreigners and if we kick them all out, you'll have nothing to watch but football and mixed martial arts, which are not the arts," she said to huge applause from the room.
She continued: "An actor's only job is to enter the lives of people who are different from us and let you feel what that feels like. And there were many, many powerful performances this year that did exactly that -- breathtaking, compassionate work."
Streep, however, said there was one "performance" this year that "stunned" her "not because it was good -- there was nothing good about it."
That, she said, was that moment when "the person asking to sit in the most respected seat in our country imitated a disabled reporter, someone he outranked in privilege, power and the capacity to fight back."
Although he was recorded doing so, Trump has denied he mocked New York Times reporter Serge Kovaleski.
"It kind of broke my heart when I saw it and I still can't get it out of my head because it wasn't in a movie, it was real life," Streep said. "This instinct to humiliate when it's modeled by someone in the public ... by someone powerful, it filters down into everyone's life because it kind of gives permission for other people to do the same.
"When the powerful use their position to bully others, we all lose."
Trump has denied he mocked New York Times reporter Serge Kovaleski in front of thousands at a rally in 2015 and reiterated his position while responding to Streep's speech.
"I was never mocking anyone," Trump said. "People keep saying I that I intended to mock the reporter's disability, as if Meryl Streep and others could read my mind, and I did no such thing."
Trump, who had not seen the speech, called Streep "a Hillary lover," according to the Times.
Streep also stumped for the press, who she said is needed to "hold power to account."
Streep asked for those in the audience to support the nonprofit Committee to Protect Journalists "because we're going to need them going forward and they're going to need us to safeguard the truth."
The actress closed her speech with a quote from her late friend Carrie Fisher: "Take your broken heart and make it into art."
On Twitter, the actress found support from her peers.
"Thank you #MerylStreep," wrote Julianne Moore in a tweet.
"Everything she said. Thank you #MerylStreep for you work and everything you said tonight," added Laverne Cox.
The response to Streep's speech wasn't all positive.
Fox News host Sean Hannity tweeted: "This is exactly why Hwood is DYING, what a bunch of hypocrites. Sex, violence, and drivel rule hwood. Turning the channel."